Opium revisited: a brief review of its nature, composition, non‐medical use and relative risks
Identifieur interne : 000864 ( Main/Exploration ); précédent : 000863; suivant : 000865Opium revisited: a brief review of its nature, composition, non‐medical use and relative risks
Auteurs : H. Kalant [Canada]Source :
- Addiction [ 0965-2140 ] ; 1997-03.
English descriptors
- Teeft :
- Acute effects, Addict, Addiction, Addiction rates, Addiction research foundation, Alcohol dependence, Alkaloid, Arsenic, Ayyangar bhide, Brief review, British journal, Cannabis, Codeine, Crude opium, Current users, Daily users, Different parts, Different regions, Dross opium, Drug abuse, Drug problems, Entire amount, Finnegan fehr, Fisher gillard, Forensic science, Free base, Frontier province, Harmless form, Heroin, Heroin addicts, Hill tribes, Illicit market, Indian opium, Intravenous injection, Jaffe martin, Kalant, Large proportion, Major effects, Martin zweben, Morphine, Morphine content, Morphine sulphate, Narcotic, Neider, Nervous system, Opium, Opium poppy, Opium pyrolysates, Opium samples, Opium smokers, Opium smoking, Oral consumption, Oral intake, Other drugs, Other parts, Pharmacological basis, Physical dependence, Pipe bowl, Poppy, Principal alkaloids, Pulmonary disease, Pure morphine, Recent years, Relative risks, Small intestine, Smoker, Smoking, Social acceptance, Substantial risks, Terry pellens, User, Westermeyer, Westermeyer neider, Wide range.
Abstract
Unlike the pure opioids such as morphine and heroin, opium is a complex and variable mixture of substances reflecting differences in both the starting material and the traditional practices of the regions in which it is produced. Analytical methods have improved greatly in recent years, to the point that the source of a preparation can often be identified by its opioid content and its impurities. Daily amounts used, both by smoking and by mouth, vary widely from less than a gram to 30 g, equivalent to 75—3000 mg of morphine. The effects of opium are essentially those of morphine but unexpected toxicities, suck as oesophageal cancer associated with “dross opium” and polyneuropathy due to deliberate addition of arsenic, are problems in some specific regions. Prevalence of use in different areas and countries is governed by the same factors of ease of availability, price and social acceptance that apply to the use of alcohol and other drugs in western countries. The risk of addiction to opium smoking appears to be somewhat less than to parenteral use of heroin, but appreciably greater than to alcohol Even in countries where its use is traditional, opium smoking carries substantial risks of harm to health and social functioning.
Url:
DOI: 10.1111/j.1360-0443.1997.tb03197.x
Affiliations:
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Analytical methods have improved greatly in recent years, to the point that the source of a preparation can often be identified by its opioid content and its impurities. Daily amounts used, both by smoking and by mouth, vary widely from less than a gram to 30 g, equivalent to 75—3000 mg of morphine. The effects of opium are essentially those of morphine but unexpected toxicities, suck as oesophageal cancer associated with “dross opium” and polyneuropathy due to deliberate addition of arsenic, are problems in some specific regions. Prevalence of use in different areas and countries is governed by the same factors of ease of availability, price and social acceptance that apply to the use of alcohol and other drugs in western countries. The risk of addiction to opium smoking appears to be somewhat less than to parenteral use of heroin, but appreciably greater than to alcohol Even in countries where its use is traditional, opium smoking carries substantial risks of harm to health and social functioning.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Kalant, H" sort="Kalant, H" uniqKey="Kalant H" first="H." last="Kalant">H. Kalant</name></noRegion><name sortKey="Kalant, H" sort="Kalant, H" uniqKey="Kalant H" first="H." last="Kalant">H. Kalant</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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